The study examined the undergraduates’ self-efficacy and self-esteem as predictors of use of library information resources in Nigeria. The research design adopted for this study was the descriptive survey design. The population for this study was 28,829 undergraduate students of Delta State University, Abraka and Novena University, Ogume. The stratified random sampling technique was used to select a sample size of 384 respondents for the study while the instrument used for data collection was a structured Questionnaire. Data was analyzed using frequency distribution tables; percentage, mean scores and standard deviation. Results showed that the self-esteem and self-efficacy of the undergraduates were at a moderate level. The most frequently used library resources were textbooks (Delsu, mean=3.49, Novena, mean=3.32). Most of the undergraduates used the library information resources for examination preparation (Delsu, mean=3.49, Novena =3.32). A significant number of the respondents were satisfied with the textbooks (Delsu, mean=3.18, Novena, mean=3.25). The greatest constraint to the use of library information resources identified by most of the respondents in Delsu was lack of proper storage and display (mean=3.18), while in Novena, it was obsolete resources (mean=3.10). The study recommended that regular training should be conducted for library users in order to ensure that they are able to use complex library resources effectively.